Wild horse chase

Wild horse chase

(pharmaceutical information)

[source] the whole plant of Eupatorium adenophorum in Compositae.

[plant morphology] Eupatorium adenophorum

Perennial herbs, 1-2 m high. Rhizome short, with fibrous roots. Stem erect. Upper branch, light brown or purplish, scattered purple spots, densely hairy when tender, less hairy when old. Leaves opposite, 3-lobed, whorled, sometimes undivided or deeply lobed, sessile, lobes linear lanceolate, margin sparsely serrate, hairs on both sides, purulent spots below, veins 3-branched. Inflorescence numerous, short stalked, arranged in close corymbose shape; involucre campanulate, bracts 9, lanceolate; each inflorescence has 5 tubular flowers, bisexual, purplish, apex 5-lobed; stamen 5-lobed; stigma 2-lobed. Achene black, elliptic and slightly flat. The flowering period is September.

On wet hillsides, meadows or streams. It is distributed in East China, South China, North China, Northeast China and Taiwan.

[collection] in autumn, when the flowers open at the beginning, they are cut and dried in the sun.

[medicinal material] the stem is cylindrical, with longitudinal edges, densely covered with gray white Tricholoma; the lower part is brown, and the upper part is slightly purplish brown; it is hard, easy to break, and the section is fibrous and white. Leaves opposite, sessile, 3-lobed, whorled; after moist flattening, middle lobe longer, linear lanceolate, margin sparsely serrate, upper green brown, lower yellow green, glandular dots visible under magnifying glass, both sides hairy. There are many flower heads or fruits at the end of the branch. It is better to have dry body, many leaves, green color and no impurity.

[chemical constituents] the whole herb contains flavonoids (Hyperoside), alkaloids, volatile oil and coumarin.

[pharmacological action] the flavonoids from Eupatorium lindleyanum L. were mixed with carboxymethyl cellulose to form a suspension, which was orally administered to mice. It had a certain antitussive effect on cough caused by ammonia. It is reported that 10% concentration has inhibitory effect on Staphylococcus aureus, Shigella dysentery and Streptococcus A. clinically, it can increase white blood cells, decrease blood pressure and inhibit gland secretion.

Bitter and smooth.

Functions and indications: clearing away heat and toxin, eliminating phlegm, calming asthma and lowering blood pressure. Treatment of chronic tracheitis, bronchitis, hypertension.

[usage and dosage] oral administration: decoction, 1-2 Liang.

[clinical application] treatment of chronic tracheitis

The clinical observation was carried out by using the whole herb of Eupatorium lindleyanum and its extracts flavonoids and alkaloids: 79 cases in the flavonoids group, 97 cases in the alkaloids group, 94 cases in the flavonoids and alkaloids mixed group, and 154 cases in the whole herb group. The dosage of each group was equivalent to 2 taels of crude drug per day, processed into various tablets, 3 times a day, 3 tablets per time, 10 days as a course of treatment, two consecutive courses. Results the total effective rate of each group was 78.7-85.5%, the near control and marked effective rate was 31.7-46.6%, and the mixed group was the best. The antitussive effect was the best, expectorant was the second, and antiasthmatic was the worst. In practice, it was observed that the curative effect of short course of disease was higher, and with the extension of the course of disease, the curative effect gradually decreased. For patients with emphysema, the curative effect seems to be lower than that without complications, but there is no statistical difference. The effective rate and near control markedly effective rate of two courses were significantly higher than those of one course. The side effects were mild dry mouth, epigastric discomfort, dizziness, etc., which were more obvious in the whole herb group, but they could disappear without affecting the continued medication. The results of routine examination of liver function and urine showed no significant changes in some patients before and after treatment. It was found that yemazhui had the effect of reducing blood pressure. For patients with hypertension, it could achieve certain therapeutic effect at the same time. For patients with normal blood pressure, it only showed fluctuations within the normal range, and no one had symptoms of hypotension.