Datura stramonium

Datura stramonium

(Lu Chuan Ben Cao)

[source] it is the root of Datura stramonium or Datura tomentosa. The plant morphology is detailed in the section of "Yangjinhua".

[chemical constituents] the root of Datura stramonium contains 0.35% and 0.37% of total alkaloids, including colchicine, amantadine, tropine and pseudotropine. The content of alkaloids is related to the thickness of the root. For example, a black variety of Datura stramonium, the diameter of the root (0.5cm, the content is 0.28% (calculated by tianxianziamine), and the content of 0.5cm, the content is 0.13-0.15%. In addition, the content of alkaloids in roots of Datura stramonium was the least. The content of alkaloids in roots was the highest at the flowering and fruiting stage (0.77%).

The content of total alkaloids in roots of M. mandshurica is 0.15-0.48%, the highest is 0.541%. The main alkaloids are amantadine, and the rest are colchicine (16% of the total alkaloids), L-3 α, 6 β - di-crotonoyloxytropine, doranine, 7-hydroxy-3,6-di-crotonoyloxytropine, pseudotropine and tropine.

The content of total alkaloids in the roots of O. mandshurica was 0.214%, 0.15% and 0.19-0.26% in the wild. The content of total alkaloids fluctuated in one day, increased gradually in the daytime, reached the highest at dusk (19 o'clock), and then decreased gradually. The alkaloids include amantadine, colchicine, erythrostigmatine, 7-hydroxy-3,6-biscrotonoyloxytropine, atropine, etc. At the later stage of plant growth, the roots contain atropine esterase, which catalyzes the transformation of atropine into tropine and tropinic acid. The optimum pH of the enzyme is 4.7-5.7 (30 ℃). The content of alkaloids in roots was the lowest.

The content of total alkaloids in the root of Datura stramonium is the least. It also contains esterase which hydrolyzes alkaloids.

[functions and indications] ① flora of Guangzhou: "it is used to treat the bite of mad dogs. "

② "Lu Chuan's Materia Medica" says: "cure evil sores. "

[usage and dosage] external use: grind the powder, mix and spread it, or decoct and wash it with water.

[prescription selection] ① for psoriasis: peel the root skin of Datura stramonium, dry it in the sun, grind it into powder, add vinegar and alum to wipe the affected area. (records of Guangxi Traditional Chinese Medicine)

② Treatment of palm itching flow yellow water: Datura fresh root three money, realgar three money, alum three money. Appropriate amount of water, fry several times, and bring to a boil. Let the patient immerse the affected part in the liquid medicine when the temperature is suitable, the longer the better, make - twice a day. (Minnan folk herbal medicine)

③ Treatment of muscle and bone pain: Datura root one or two, half a jin of wine. Ten days later, drink one or two times a day for no more than one dollar each time. (main poisonous plants in South China)