Dogfoot root

Dogfoot root

(abstracts of 1962 academic conference of Chinese Pharmaceutical Association)

[source] it is the root of Schima superba.

[plant morphology] Schima superba, also known as xingmangkeli.

Evergreen trees, 4-6m high. Branchlets brown. Leaves alternate, leathery; elliptic, 6-10 cm long, 3.5-4.5 cm wide, apex obtuse, base obtuse or rounded, entire, glabrous on both sides, scattered with tiny glandular dots; petiole 7-10 mm long. Panicle terminal, puberulent, 20 cm long; bracts and 2 bracts are conical; peduncle 2-3 mm long; flowers white, fragrant; sepals 5, broadly ovate, 1 mm long, apex apiculate, base slightly connate, puberulent; corolla cylindric, 3-4 mm long, lobes 5, triangular, puberulent; stamens 10, not protruding, filaments abruptly reflexed; ovary 5-locular, puberulent Style terete, stigma truncate. Capsule globose, 9-10 mm long, 5-angled, locular dorsal dehiscence 5-valved; seeds 4-7, winged on one side. The flowering period is September. The fruit period is from October to November.

Born in the forest. It is distributed in Yunnan.

[collection] dig out the roots, wash them, slice them and dry them in the sun.

[chemical constituents] it contains Crotalaria toxin.

[pharmacological action] the anti-inflammatory effect of Crotalaria toxin (0.8 mg / kg) was stronger than that of cortisone acetate (50 mg / kg) or sinomenine (50 mg / kg). The median lethal dose of the toxin was 1.79 mg / kg. Poisoning symptoms such as lying on the ground, vomiting and paroxysmal spasm are similar to those of crude drug extract.

The ethanol extract, isolated white crystal and white powder of Cynanchum dactylon were orally administered 500, 1.25 and 3.75 mg / kg to rats, respectively, which had significant inhibitory effect on egg white arthritis. After oral administration of ethanol extract, the content of vitamin C in adrenal gland of rats was significantly decreased, indicating that its anti-inflammatory effect may be related to the excitation of adrenal cortex function. The median lethal dose of ethanol extract was 5.62 ± 0.42 g / kg. The respiration stopped before the heart and the heart stopped in diastole.

[function indications] anti inflammatory, analgesic. Treat rheumatism joint ache. (abstracts of 1962 academic conference of Chinese Pharmaceutical Association)

[choice] acute, chronic strain of low back pain, low back pain: the root of the dog's foot grass is seven to one yuan (fresh doubles), fresh pine tip five to six, Baijiu one or two. Take it while it's hot when boiling until the amount of alcohol is half. Take it three times in a row if you are seriously ill. (Kunming)