Yang Menghua

Yang Menghua

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Yang Menghua, female, born in March 1978. Macao, China, native of Jiangmen, Guangdong. Doctor, Professor of animal science and Technology College, Zhejiang agriculture and Forestry University.

Educational experience

2005 / 9-2008 / 7: doctor, Nanjing Agricultural University, Academy of life sciences, 2002 / 9-2005 / 7: Master, China Agricultural University, Academy of life sciences, 1997 / 9-2001 / 7: Bachelor, China Agricultural University, Academy of life sciences

work experience

From February 2013 to now, Professor of School of animal science and technology of Zhejiang agriculture and Forestry University from August 2009 to January 2013, postdoctoral researcher of University of Pennsylvania, School of medicine from July 2008 to August 2009, assistant researcher of Lehman College, City University of America

Research direction

1. Expression regulation mechanism of Vibrio cholerae toxin gene 2. Interaction between intestinal pathogens and conditional pathogens 3. Discovery of unknown proteins in quorum sensing

Lead the project

1. Research on the regulation mechanism of Vibrio cholerae aphB protein on oxygen chemotaxis, talent start project, 2013-2016, with a fund of 500000 yuan. 2. Research on the regulation mechanism of Vibrio cholerae aphB protein on oxygen chemotaxis, NSFC general program, Youth Science Foundation, 2014-2016, funding 230000 yuan . 3. Research on molecular regulation mechanism of bile acid mediated gene expression of Vibrio cholerae toxin, NSFC, 2015-2018, funding 850000 yuan

Published articles

1.YangM.H.,LiuZ.,HughesC.,SternA.,WangH.,ZhongZ.T.,KanB.,FenicalW.,ZhuJ.2013.Bilesalt-inducedintermoleculardisulfidebondformationactivatesVib riocholeraevirulence.Proc.NatlAcad . Sci.USA .(IF9.8)110(6):2348-2353 2.LiuZ.*,YangM.H.*,PeterfreundG.L.,SelamogluN.,DaldalF.,ZhongZ.T.,KanB., ZhuJ.2011.Vibriocholeraeanaerobicinductionofvirulencegeneexpressioniscontrolledbythiol-basedswitchesofvi rulenceregulatorAphB.Proc.NatlAcad . Sci.USA (if9.8) 108 (2): 810-815 * co first author: Yang M.H., Frey E.M., Liu Z., bishar R, andZhuJ.2010.ThevirulencetranscriptionalactivatorAphAenhancesbiofilmformationofVibriocholeraebyactivatingtheexpressionofthe biofilmregulatorVpsT.InfectionandImmunity .(IF4.1)78(2):697-703 4.YangM.H.,GielJ.L.,CaiT.,ZhongZ.T., ZhuJ.2009.TheLuxR-familyquorumsensingactivatorMrtRrequiresitscognateautoinducerfordimerizationandactivationbut notforproteinfolding.JBacteriol .(IF3.7)191(1):434-438 5.YangM.H.,SunK.J.,ZhouL.,YangR.F.,ZhongZ.T., ZhuJ.2009FunctionalanalysisofthreeAHLautoinducersynthasegenesinMesorhizobiumlotirevealstheimportantroleofquorumsensingi nsymbioticnodulation.CanadianJournalofMicrobiology (IF1.2)55(2):210-214 6.CaoH.J.*,YangM.H.*,ZhengH*.M.,ZhangJ.,ZhongZ.T., ZhuJ.2009.ComplexquorumsensingregulatorysystemsregulatebacterialgrowthandsymbioticnodulationinMesor hizobiumtianshanense.ArchivesofMicrobiology (if1.8) 191 (3): 283-289 * co first author: 7. Luh. Y., Luo L., Yang M. H., Cheng H. P. 2012sinorhizobium meliloti exoristhe target of PE riplasmicproteolysis.JBacteriol .194(15):4029-4040 8.YangM.H.,ZhongZ.T., ZhuJ.2006.RecombinantexpressionofanautoinducersynthaseofMesorhizobiumlotiinEscherichiacoliandanalysisoftheautoinducerproduce dinrecombinantstrain.JournalofMicrobiology (Chinese)46(6):1007-1010 9.YangM.H.,LiY., GuanG.H.2005.High-levelExpressionofanextreme-thermostablexylanaseBfromThermotogamaritimaMSB8inEscherichiac oliandPichiapastoris.JournalofMicrobiology (Chinese)45(2):236-240