Zishi

Zishi

(Modern Practical Chinese Medicine)

[source] it is the fruit of Bignoniaceae. For plant morphology, please refer to "zibaipi".

[collection] the mature fruits were picked in autumn and winter and dried in the sun.

[herbal medicine] capsule is narrow linear, strong adhesion when fresh, and gradually disappear when ripe. It is 20-30 cm long, 5-9 mm thick, slightly curved, dark brown or even black brown, with fine longitudinal wrinkles and glossy spots, rough and brittle. Fruiting stipe at base. Apex often ruptured, exposing seeds. Seed light brown, thin, 5 mm long, 2-3 mm wide, 1 cm long at both ends of the white luster hairy, central inner surface with dark umbilicus. After the seed coat is removed, it is the embryo with 2 cotyledons. It is almost tasteless and slightly convergent.

Produced in Hunan, Hebei, Sichuan and other places.

[chemical constituents] the fruit contains Catalpol, dep-p-hydroxybenzoylcatalpol, p-hydroxybenzoic acid, citric acid and wax. The seeds contain p-hydroxybenzoic acid. β - sitosterol and fatty acids.

[pharmacological action] the water-soluble extract, pericarp and seed extract of Zishi have diuretic effect on mice and rabbits, and increase the discharge of electrolyte. A diuretic glycoside was proposed from catalpa seeds. In the diuretic experiment of rats, the effect of dep-p-hydroxybenzoylcatalpol was stronger than Catalpol. The former was mainly characterized by sodium diuresis, and the latter by chlorine diuresis. The diuretic effect of the two glycosides was weakened in rats with acidic urine, and increased in rats with alkaline urine. Both glycosides showed natriuretic effect in rats with bilateral adrenalectomy. It has no inhibitory effect on carbonic anhydrase and little effect on circulatory system. The toxicity is weak. Its diuretic effect is due to its effect on renal tubules.

[nature and taste] Modern Practical Chinese medicine: "sweet, flat, non-toxic. "

[functions and indications] ① modern practical Chinese medicine: "diuresis, treatment of edema. "

② "Chinese medicine and plant atlas": external use of insecticidal. "

[selected formula] for chronic nephritis, edema and proteinuria: Zishi Wuqian, decoction. (Hebei Traditional Chinese medicine manual)