Wo Er Qi

Wo Er Qi

(Shaanxi Chinese herbal medicine)

[synonym] a'erqi, wo'ershen, Shanhe ye (Shaanxi Chinese herbal medicine).

[source] it is the rhizome of the leaves of Chinese mountain Lotus (Berberidaceae).

[plant morphology] lotus leaf

Herbs perennial, up to 50 cm tall. Rhizome transverse, stout, with a row of pits, with many fibrous roots. 1 basal leaf, large, broad kidney shaped, 2-lobed, long petiole, shield shaped; 2 cauline leaves alternate, isomorphic with basal leaf, but smaller, margin dentate and slightly notched. The flowers are white, terminal cyme with long peduncle; sepals 6, caducous; petals and stamens 6; ovary superior, composed of 1 carpel; ovules 5-6. Berry globose, ca. 10 mm long, bluish black; with several seeds.

It grows on the hillside in the shade or under the mountain forest. It is distributed in Shaanxi, Gansu, Sichuan, Hubei, Yunnan and other places.

[collection] in autumn.

[chemical constituents] the root contains podophyllin, dihydropodophyllin and kaempferol. Kaempferol, quercetin, podophyllin, β - deswater podophyllin, kaempferin, podophyllin, podophyllin, dehydrogepodophyllin, deswater podophyllin, kaempferin and podophyllin are lignans. This kind of substance was originally separated from podophyllum resin and has been noticed for its inhibitory effect on tumor cells.

[pharmacological action] the action of podophyllin is similar to colchicine. It is very sensitive to experimental sarcoma and cancer cells, but it is not used as an anticancer agent because of its great toxicity to human normal cells (podophyllin derivatives are used as anticancer agents in clinic). When applied to skin, it can cause abnormal division of basal epidermal cells, degeneration of protoplast and nucleus. The oil solvent or alcohol solvent can be used to remove condyloma acuminatum or mastoid wart. At this time, attention should be paid not to make the liquid contact with healthy skin. Oral administration of podophyllum cable or podophyllum resin can stimulate the small intestine and produce a large amount of watery diarrhea, which belongs to resin cathartic; at this time, it is often accompanied by abdominal pain, large amount, and even bloody stool, or lead to severe exhaustion collapse. Injection of podophyllin has great toxicity, which first shows its stimulating effect on the central nervous system. The sensitivity of animals to podophyllin is different. Cat is the most sensitive, and it is easy to cause vomiting and diarrhea (chlorpromazine has some preventive effect on these toxic reactions); rats, guinea pigs and dogs are less sensitive. Except guinea pig and duodenum. In mice (sensitized by allogeneic red blood cells), podophyllin has the effect of immunosuppression. After injection, some metabolites were excreted in urine, but not in original form. Daily subcutaneous injection can produce accumulation effect. The median lethal dose of podophyllin was 30-35 mg / kg.

[nature and taste] Shaanxi Chinese herbal medicine: "bitter, cold, poisonous. "

[functions and indications] ① Shaanxi Chinese herbal medicine: "dispelling wind and dampness, clearing heat and cooling blood, promoting blood circulation and relieving pain, and having purgative effect. It is used to treat rheumatoid arthritis, lumbocrural pain, bone steaming, fatigue heat, traumatic injury, irregular menstruation, less abdominal pain, carbuncle swelling. "

② "Selected Chinese herbal medicine of Shaanxi, Gansu, Ningxia and Qinghai": dispelling wind and dampness, breaking blood stasis, relieving pain and detoxification. "

[usage and dosage] oral administration: decoct soup, 1-3 yuan; make powder or soak wine. External use: powder compress.

[taboo] Shaanxi Chinese herbal medicine: "do not use hot substances; do not use it in pregnant women. "

[prescription selection] ① for the treatment of rheumatic lumbago and leg pain: wo'erqi, Changchun Qi, zhushalian and Weilingxian are three yuan each, and podophyllum is one yuan and five Fen each. Take it in water.

② Treatment of traumatic injury, irregular menstruation, abdominal pain: Wo Er Qi Yi Qian. Take it at the end of the study, twice a day.

③ Treatment of carbuncle, sore and furuncle: at the end of the Seventh Research of wo'er, apply wine and vinegar to the local area.

④ Treatment of snakebite: Wo Er 73 Qian. Decoct with water, mash the dregs of the medicine, and apply the wine to the affected area. (the selected prescription is selected from the selection of Chinese herbal medicine of Shaanxi, Gansu, Ningxia and Qinghai)