Cottonseed oil

Cottonseed oil

(compendium)

[source] it is fatty oil extracted from seeds of Malvaceae plant Gossypium hirsutum. See "cotton" for plant morphology.

[chemical constituents] the seed oil contains linoleic acid (41-45%), palmitic acid (20-25%), oleic acid (30-35%), stearic acid and other glycerides and phytosterols, and the crude oil contains gossypol.

[pharmacological action] cottonseed oil can increase the level of blood lipids in chickens, which is higher than other vegetable oils (such as corn oil, sunflower oil, etc.); it may be that it contains cyclopropene fatty acids, which can increase the serum cholesterol level, aortic atherosclerosis, and promote the excretion of bile, but the cholesterol content in liver is lower, so it may promote the cholesterol autogenous metabolism The liver moves to the blood and bile. The effect of cottonseed oil on cardiovascular disease in mice was also higher than that of corn oil. The median lethal dose of cottonseed oil was 255 ± 22 ml / kg and the maximum tolerable dose was 203 ml / kg. There were systemic capillary venous stasis, erythrocyte disintegration, capillary hemorrhage, water loss, visceral weightlessness, gastric large cell infiltration ulcer, renal tubular and skeletal muscle degeneration. In the chronic toxicity test, 6 or 9 g / kg of cottonseed oil suspension was given intravenously to dogs, which caused them to die on the 15th and 5th day respectively, while the same dose of soybean oil did not cause any harm. See "cotton root" for toxicity.

[nature and taste] Compendium: "pungent, hot, slightly toxic. "

[functions and indications] the Compendium: "it is used to treat vices and scabies (external application). "