High goats don't eat

High goats don't eat

(commonly used Chinese herbal medicine in Sichuan)

[synonym] Shanxiang (commonly used Chinese herbal medicine in Sichuan).

[source] it is the root and rhizome of Corydalis elliottii.

[plant morphology] Corydalis elliottii

Perennial herbs, 50-100 cm high. The rhizome is thick with yellow cross section. Stem erect or upper part slightly oblique, pilose. 1-3 pinnate compound leaves, alternate; basal leaves with long stalks; leaflets papery, obovate or ovoid, 3-lobed or feathered, green above, gray green or green white below. Raceme terminal or apical leaf axillary; bracts lanceolate; sepals elliptic. Purple after drying, with irregular deep lobes on the upper part; corolla red purple or blue, petals 4, upper petals base spaced; stamen 6; pistil 1, ovary superior, 1-locular, style slender, stigma 2-lobed. Capsule, oblong elliptic, 2-valved, style persistent. Seeds small, suborbicular, black, glossy. The flowering period is from May to June. The fruit period is from July to March.

It grows at the edge of the ditch and under the forest. It is distributed in Sichuan and other places.

[collection] in summer and autumn, they were dug and dried in the sun.

[chemical constituents] the root contains alkaloids.

[pharmacological action] analgesic effect. Hot plate, electric stimulation, chemical stimulation and photothermal stimulation were used to prove the analgesic effect of Shanxiang alkaloid B on mice, rats and rabbits. Due to the different experimental methods, animal species and drug overdose, the analgesic effect showed considerable differences, such as hot plate method in mice, subcutaneous injection. The effect of this product is equal to that of morphine, but its lasting time is less than that of morphine. However, when the mice were given chemical stimulation, the effect of the drug was only 1 / 10 of that of morphine. In general, the analgesic effect of this product is not as good as that of morphine, but it appears and disappears very quickly. It may be because the product is easy to be destroyed in the body. The alkaloids a, C, D and e of Daphne odorifera don't have analgesic effect, and can easily cause convulsion and death in mice.

[toxicity] the median lethal dose of Shanxiang alkaloid B was 99.12 mg / kg by intravenous injection and 1200 mg / kg by subcutaneous injection in mice. After intraperitoneal injection of 1 000 mg / kg and 1 500 mg / kg, deep inhibition, righting reflex disappeared, deep and slow breathing, but no death occurred.

[nature and taste] common Chinese herbal medicine in Sichuan: "bitter, slightly cold, with little poison. "

[functions and indications] common Chinese herbal medicine in Sichuan: "clearing heat, relieving pain, eliminating rheumatism. Treatment of heart and stomach qi pain, gallbladder heat disease. "

[usage and dosage] oral administration: decoction, 1-2 yuan.