Whitney
Whitney
Huidi (mesalazine enteric coated tablets), indications for ulcerative colitis, segmental ileitis (Crohn's disease).
Warning
It is forbidden to be allergic to salicylic acid drugs and excipients.
Ingredients
Mesalazine.
Chemical name: 5-aminosalicylic acid.
The chemical structure formula is: < br > < br > molecular formula: C < sub > 7 < / sub > H < sub > 7 < / sub > no < sub > 3 < / sub > < br > molecular weight: 153.14
character
This product is enteric coated tablets. After removing the coating, it appears white to reddish.
indication
Ulcerative colitis, segmental ileitis (Crohn's disease).
Specifications
0.25g
Usage and dosage
Adult: ulcerative colitis: < br > < br > (acute attack) 4 times a day, 1g (4 tablets) each time, or as directed by the doctor.
(maintenance treatment) 0.5g (2 tablets) 3 times a day, or as directed by the doctor.
Segmental ileitis: 1g (4 tablets) 4 times a day, or as directed by the doctor.
Adverse reactions
May cause slight stomach discomfort. Occasionally nausea, headache, dizziness, etc.
taboo
It is forbidden to be allergic to salicylic acid drugs and excipients.
matters needing attention
1. Use with caution in patients with renal or liver dysfunction. Discontinue use in case of rash and consult your doctor as soon as possible.
2. Swallow, do not chew or crush. If one dose is missed for some reason or forgotten, it should be taken as soon as possible or at the same time with the next dose.
Medication for pregnant and lactating women
There are few data on teratogenicity. Pregnant and lactating patients should use this product with caution.
Medication for children
Children under two years old should not use this product, children over two years old: 20 ~ 30mg / kg, or follow the doctor's advice.
Medication for the elderly
The use of this product in elderly patients should be reduced.
Drug interactions
If taking this product and taking cyanocobalamide tablets at the same time, it will affect the absorption of cyanocobalamide tablets.
Drug overdose
There are few data in excess of the study. A 3-year-old child mistakenly took 2G of this product, and no accident occurred after vomiting induction and active carbon treatment. The risk of overuse is rare.
Pharmacology and Toxicology
Most of the drugs can reach the colon, act on the inflammatory mucosa, inhibit the synthesis of prostaglandins and the formation of leukotrienes, which cause inflammation. It has a significant anti-inflammatory effect on the inflammation of the intestinal wall, especially on the inflammatory connective tissue of the intestinal wall.
Pharmacokinetics
After oral administration, the drug is released in the ileum and colon, and only a small amount of drug is absorbed into the blood. The drug entering the blood mainly forms acetylsalicylic acid metabolite through the first pass effect metabolism of liver, and its average binding rate with plasma protein is 83%. Acetylated metabolites were excreted from the urethra, and the unabsorbed drugs were excreted with feces.
Storage
Keep out of light and sealed.
packing
Double aluminum packaging, 12 pieces per plate, 2 plates per box.
term of validity
24 months
Executive standard
WS1-(X-038)-2003Z
Approval number
Guoyao Zhunzi h19980148
manufacturing enterprise
Jiamusi Luling Pharmaceutical Co., Ltd
Date of approval
December 22, 2006
Whitney